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The Scotsman, a semifinalist for the last two years, next takes on Croatian veteran Ivan Ljubicic for a place in the last 16.
"I served well today, but the rest of my game needs some work," said Murray after his Court One workout.
Three-times runner-up Andy Roddick, the eighth seed, also eased through, defeating Romania's Victor Hanescu 6-4, 6-3, 6-4 and next plays Spain's Feliciano Lopez.
Heavy morning rain meant a three-hour delay to action away from the covered Centre Court with Swiss 14th seed Stanislas Wawrinka and Juan Ignacio Chela, the Argentine 25th seed left the tournament.
Wawrinka went down 7-6 (7/5), 6-3, 7-6 (7/4) to Italian lucky loser Simone Bolelli, the Italian world 116, while Chela went out 6-0, 6-3, 6-4 to Alex Bogomolov of the United States.
Czech sixth seed Tomas Berdych, last year's runner-up, defeated France's Julien Benneteau 6-1, 6-4, 6-2.
French player Gael Monfils, the ninth seed, also made it through with a 4-6, 6-3, 6-3, 7-6 (9/7) win over Slovenia's Grega Zemlja.
American 10th seed Mardy Fish eased past Denis Istomin of Uzbekistan 7-6 (8/6), 6-4, 6-4 while 2007 semifinalist Richard Gasquet, the French 17th seed, beat Russia's Igor Kunitsyn 6-1, 6- 4, 6-4.