What do you mean? 你什么意思？接下来讲解。例句：
1. Iris：What do you mean by that?艾瑞丝：你那样说是什么意思？
2. What do you mean by saying so?你这么说什么意思?
3.What do you mean we have no more milk. I just bought some yesterday.我们的牛奶又没了，你什么意思，我昨天刚买的。
